Sensitive ChIP-DSL technology reveals an extensive estrogen receptor -binding program on human gene promoters
نویسندگان
چکیده
*Department of Cellular and Molecular Medicine, University of California at San Diego School of Medicine, La Jolla, CA 92093-0651; †Department of Medicine, Howard Hughes Medical Institute and University of California at San Diego School of Medicine, La Jolla, CA 92093; ‡Bioinformatics Graduate Program, University of California at San Diego, La Jolla, CA 92093; §Aviva Systems Biology Corporation, San Diego, CA 92121; and ¶Illumina Inc., San Diego, CA 92121
منابع مشابه
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters.
ChIP coupled with microarray provides a powerful tool to determine in vivo binding profiling of transcription factors to deduce regulatory circuitries in mammalian cells. Aiming at improving the specificity and sensitivity of such analysis, we developed a new technology called ChIP-DSL using the DNA selection and ligation (DSL) strategy, permitting robust analysis with much reduced materials co...
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تاریخ انتشار 2007